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New Products: Jan 19, 2010


CLC Bio has released CLC Genomics Server 2.0, an enterprise platform for next-generation sequencing data analysis. The new version has a number of additions, including parallelization of jobs on multiple computers, integration of third-party command-line tools and algorithms through a graphical user interface, support for file sharing and data management, and additional high-throughput sequencing analyses including digital gene expression, de novo assembly, reference assembly, SNP & DIP detection, and ChIP-seq analysis.

The platform comprises desktop applications, server software, and centralized data sharing and data management. It also includes an application programming interface for integration and custom plug-in development.

Nvidia launched the Tesla Bio Workbench, a suite of bioscience and bioinformatics applications for molecular dynamics and quantum chemistry-based research. The workbench has been designed to run complex simulations in fields such as DNA sequencing and drug discovery on a standard PC. The company said the workbench is 10 to 20 times faster than other simulations.

Currently available bioscience applications include AMBER, GROMACS, LAMMPS, NAMD, TeraChem and VMD, while bioinformatics applications including CUDA-SW++ (Smith-Waterman), GPU-HMMER, and MUMmerGPU will be available next month.

The workbench also includes a community site where users can download applications, read academic papers, and join discussion forums.

Epicentre Biotechnologies released Nextera kits designed to prepare libraries for Illumina sequencers. The announcement follows on a previous launch of Nextera kits that were designed for Roche 454 GS FLX and Titanium sequencers. The kits enable library preparation from 50 ng of DNA in under two hours and they use Epicentre's transposon-based technology to randomly fragment the template DNA and tag the ends in a single-tube reaction.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.