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New Products: Jan 5, 2010

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GenBank release 175.0 is now available here via FTP from the National Center for Biotechnology Information. It contains data as of Dec. 15, 2009. The new release comprises approximately 110 gigabases and 113 million entries from non-WGS, non-CON sequences, and 158 gigabases and 54 million entries from WGS sequences.

Uncompressed, the 175.0 release flat files require about 422 GB for sequence files only. The ASN.1 data require approximately 381 GB.

The Scan

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies on 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.