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New Products : Jan 27, 2009

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Illumina has released new sequencing chemistry kits and software, as well as a new mate pair library preparation kit, for its Genome Analyzer.

According to the company, the new chemistry kits and software increase the number of reads per run by 40 percent and extend the read length to more than 75 base pairs.

The new mate pair library preparation kit allows users to generate paired-end libraries with 2- to 5-kilobase inserts and is complementary to Illumina's existing short-insert paired-end libraries, which have 200- to 500-base inserts.

According to the company, the new releases enable researchers to generate 10 to 15 gigabases of high-quality data per run on the GA.


Roche NimbleGen has launched a Sequence Capture 2.1M Human Exome microarray. The new array targets approximately 180,000 human protein coding exons and about 700 miRNA exons. Built on the company’s HD2 platform, the array carries 2.1 million oligonucleotides greater than 60 nucleotides in length. It is based on the April 30, 2008, build of the Consensus CDS database project, an effort to identify a core set of high-quality human and mouse protein-coding regions.

According to the company, the new arrays are optimized for subsequent sequencing of captured exons on the Genome Sequencer FLX from Roche’s 454 Life Sciences, using the GS FLX Titanium chemistry.


SoftGenetics said that its NextGene software now includes a de Bruijn graph method for the assembly of paired read data from second-generation sequencers such as the Applied Biosystems SOLiD and the Illumina Genome Analyzer. The method uses short words instead of entire reads as indexes to develop the graph, reducing redundancy. The assembly technique is able to produce contigs greater than 100 kilobases in length, according to SoftGenetics.


MicroPep, a division of Precision Engineered Products, said it has fabricated its first Microwell Array, a slide with 42 million wells that are each 3 micrometers in size. The company said the array will be used for biomedical assays such as DNA sequencing.

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.