Biomatters has released Geneious 4.7 beta, a new version of its bioinformatics sequence analysis platform. Version 4.7 includes a new DNA sequence assembler that allows users to align sequences generated on the Sanger and 454 platforms to a reference genome. It is the first of three planned releases that will provide increasing support for next-generation sequence data. The next release will support data from the Applied Biosystems SOLiD and the Illumina Genome Analyzer II. Other new features of Geneious 4.7 include complete import of Vector NTI files, query-centric alignment, a primer database, 454 import and handling, keyboard shortcuts, dynamic DNA translation to protein for any selection, structure and ORF prediction on alignments, and multi-region sequence selection.