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New Products: Jun 30, 2009

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Biomatters has released Geneious 4.7 beta, a new version of its bioinformatics sequence analysis platform. Version 4.7 includes a new DNA sequence assembler that allows users to align sequences generated on the Sanger and 454 platforms to a reference genome. It is the first of three planned releases that will provide increasing support for next-generation sequence data. The next release will support data from the Applied Biosystems SOLiD and the Illumina Genome Analyzer II. Other new features of Geneious 4.7 include complete import of Vector NTI files, query-centric alignment, a primer database, 454 import and handling, keyboard shortcuts, dynamic DNA translation to protein for any selection, structure and ORF prediction on alignments, and multi-region sequence selection.

The Scan

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.

Study Looks at Parent Uncertainties After Children's Severe Combined Immunodeficiency Diagnoses

A qualitative study in EJHG looks at personal, practical, scientific, and existential uncertainties in parents as their children go through SCID diagnoses, treatment, and post-treatment stages.

Antimicrobial Resistance Study Highlights Key Protein Domains

By screening diverse versions of an outer membrane porin protein in Vibrio cholerae, researchers in PLOS Genetics flagged protein domain regions influencing antimicrobial resistance.

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.