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New Products: May 19, 2009


Scientists at the Department of Energy Joint Genome Institute and the Biological Data Management and Technology Center at Lawrence Berkeley National Laboratory have launched the Expert Review version of the Integrated Microbial Genomes system. IMG ER provides curation tools that enable researchers to review and revise annotations of microbial genomes.

As of April, the IMG system contained 1,284 bacterial, 59 archaeal, 49 eukaryotic, and 2,524 viral genomes, as well as 924 plasmid sequences. IMG ER curation tools allow researchers to detect and correct annotation problems, such as genes missed by gene prediction pipelines or genes without an associated function. The IMG ER system can be accessed here after requesting an account.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.