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New Products: Nov 29, 2011

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Researchers from the University of California, Berkeley, and the University of Maryland have released version 1.2.0 of the transcript assembly software Cufflinks here. The new release fixes several bugs and includes accuracy and performance improvements.


The National Center for Biotechnology Information has released its Variation Reporter Tool to match variant calls with variants in dbSNP or dbVar. The new tool is available here, and will provide detailed information on known alleles for the variant call. If the variant is not present in either database it will calculate whether it has a predicted functional consequence.

The NCBI has also added human variant call format files and human genotype XML files by gene to dbSNP, available here via FTP.


Researchers from Johns Hopkins School of Public Health have released Bowtie version 2.0 for aligning sequence reads to the reference. The new release, available here, includes accuracy improvements, speed improvements, and fixes several bugs.

The Scan

And For Adolescents

The US Food and Drug Administration has authorized the Pfizer-BioNTech SARS-CoV-2 vaccine for children between the ages of 12 and 15 years old.

Also of Concern to WHO

The Wall Street Journal reports that the World Health Organization has classified the SARS-CoV-2 variant B.1.617 as a "variant of concern."

Test for Them All

The New York Times reports on the development of combined tests for SARS-CoV-2 and other viruses like influenza.

PNAS Papers on Oral Microbiome Evolution, Snake Toxins, Transcription Factor Binding

In PNAS this week: evolution of oral microbiomes among hominids, comparative genomic analysis of snake toxins, and more.