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New Products: Sep 20, 2011


Integromics has launched the second version of its SeqSolve software for analyzing next-generation sequencing data. The latest version features proprietary annotations and new applications for ChIP-seq and RNA-seq — including alternative splicing, significant new gene discovery, and transcript-level differential expression, according to the company.

has released Lasergene 9.1, a software upgrade, which now includes desktop computer support for genome-wide association studies using next-generation sequence data and the integration of protein sequence, structure, and bioinformatics method capabilities in one application.

Axeq Technologies has launched its Exome Turnkey Discovery service, which aims to find disease-causing variants through exome sequencing and analysis. The service, launched at an introductory price of $9,000, combines 75-fold coverage exome sequencing of a family trio with analysis services that include data filtering and mapping, variant filtering, determination of putative candidates, and Sanger sequencing services for further validation.

The company is also now offering a whole-genome sequencing service in conjunction with array-CGH to detect copy number variation. It utilizes its Axeq-CNV array, a custom designed array that contains 180,000 probes and was jointly developed by researchers at the Genome Medicine Institute at the Seoul National University.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.