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New Products: Aug 23, 2011

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GenBank release 185.0 is available here via FTP from the National Center for Biotechnology Information. It contains data as of Aug. 14, 2011. The new release comprises approximately 131 gigabases of data from 142 million entries of non-whole genome sequencing, non-CON sequences and around 208 gigabases from 65 million entries from whole-genome sequences. Uncompressed, the release 185.0 flatfiles require around 511 gigabases. Since the previous release in June, the non-WGS/non-CON portion grew by 1.5 gigabases, increasing the number of entries by 1.8 million. An additional 970,764 records were updated.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.