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New Products: Jun 28, 2011

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Roche's 454 Life Sciences has launched its new GS FLX+ system, which can generate read lengths up to 1,000 base pairs due to an increase in the number of sequencing flow cycles and the optimization of the chemistry and software. Along with the increased read length, the system also has a 50 percent increase in throughput, according to the company. The new system is compatible with the GS FLX Titanium sequencing chemistry.

In Sequence reported on the company's plans to launch the new system last month (IS 5/24/2011).


Gene Codes has released Sequencher 5.0, which now offers alignment tools as well as SNP and methylation analysis for next-generation DNA sequence data. The new release is compatible with data from capillary electrophoresis sequencing, as well as the Roche 454, Illumina, and Life Technologies SOLiD and Ion Torrent PGM NGS platforms.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.