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NEW YORK (GenomeWeb) – Two new studies that used single-cell RNA sequencing to profile tracheal or bronchial tissue from mice or humans have provided a clearer understanding of the relationships between cells in the airway and lungs, while identifying a new cell type that appears to be relevant to cystic fibrosis biology.

"The atlas that we've created is already starting to drastically reshape our understanding of airway and lung biology," Aviv Regev, director of the Broad Institute's Klarman Cell Observatory and co-chair of the Human Cell Atlas consortium, said in a statement.

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In PNAS this week: links between lung adenocarcinoma and lncRNA, algorithm to impute and cluster Hi-C interaction profiles from single cells, and more.

Jul
23
Sponsored by
Qiagen

This webinar will discuss how the Molecular Pathology Laboratory at the University of Oklahoma (OUMP) is using a new quality improvement model to support molecular testing of oncology patients. 

Jul
30
Sponsored by
Mission Bio

This webinar will outline a project that performs large-scale and integrative single-cell genome and transcriptome profiling of pediatric acute lymphoblastic leukemia (ALL) cases at diagnosis, during drug treatment, and in case of relapse.