NEW YORK (GenomeWeb) – A team from the Netherlands identified 10 new candidate genes for intellectual disability through a meta-analysis of de novo mutations in exome sequences from thousands of affected families.

Starting with exome sequences generated through Radboud University Medical Center's genetic testing program for 820 children with mild to severe intellectual disability and their parents, the researchers subsequently folded in information from nearly 1,300 other parent-child trios sequenced for published studies.