New Base Caller Improves Accuracy of Long Illumina Reads; May Allow De Novo Assembly | GenomeWeb
Researchers at Cold Spring Harbor Laboratory have developed a new base caller for the Illumina Genome Analyzer and have used it to increase the number of accurate long reads per run.
The Alta-Cyclic base caller enabled the researchers to increase the number of accurate 78-base reads in a run from 5 percent to 22 percent. These reads, they say, may allow them to assemble complex eukaryotic genomes de novo.

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