New Assembly Method Addresses Challenges of Short-Read Single-Cell Sequencing | GenomeWeb

By Andrea Anderson

Researchers from the University of California at San Diego, the J. Craig Venter Institute, and Illumina Cambridge have designed a genome assembly method to deal with non-uniform sequence data generated during single-cell genome sequencing.

"Our approach enables acquisition of genome assemblies for individual uncultivated bacteria using only short reads," the study authors wrote, "providing cell-specific genetic information absent from metagenomic studies."

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