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NCRR Grants Six Academic Centers $7M to Help Buy Tools for Genomic, Proteomic Research

NEW YORK (GenomeWeb News) — The National Center for Research Resources has spent more than $7 million to help six US academic centers buy high-end instruments, including mass spectrometers and sequencers for genomics proteomics research, the NCRR said today.

The awards are part of $21 million in grants the NCRR is distributing to 14 academic centers in the US under the High-End Instrumentation grant program. In order to receive the HEI grants, which are limited to equipment costing between $750,000 and $2 million, institutions must have three or more NIH-funded investigators involved in research that required the equipment. 
 
Awards for genomic and proteomic technologies include:
  • $928,365 for Johns Hokins University to buy a hybrid linear ion-trap mass spectrometer to help it study ischemia and hypoxia, and “networks and pathways of lysine modifications and the structural analysis of carbohydrates.” 
     
  • Yale University has received $1.2 million to purchase DNA sequencing/genotyping technologies to help it study the genomics of epilepsy, psychiatric disorders, autism, cardiovascular disorders, and cancer. 
     
  • The University of Arizona was granted $924,995 to buy a hybrid quadrupole Fourier transform ion cyclotron resonance mass spectrometer with high-throughput, high-resolution, and high-mass accuracy and equipped with electron capture dissociation and infrared multiphoton dissociation. The researchers will use the technology to study proteins and protein complexes, post-translational protein modifications, polyamines important in colorectal cancer, and other projects.
     
  • The Health Sciences Center at the University of Colorado at Denver received a $1.1 million grant to buy a linear ion trap-Fourier transform ion cyclotron resonance mass spectrometer for cancer studies and other research. 
     
  • The School of Medicine and Dentistry at the University of Connecticut obtained a $2 million grant to buy an 800 MHz nuclear magnetic resonance spectrometer for studies involving “proteins that participate in repair at sites of DNA damage,” “proteins that function as tumor suppressors and their mutants,” and “enzymes involved in antibiotic resistance.” 
     
  • The University of Washington received a $1 million grant to acquire a pulsed electron paramagnetic resonance/X-band electron nuclear double resonance spectrometer to help study enzyme function, structural proteins, and proteins at DNA and RNA interfaces. 
An NCRR spokesperson said the grants were disbursed at the end of May.
 
Additional information about the current HEI program can be found here.

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