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Natera, Feinstein Institute Partner on Noninvasive Cancer Diagnostics Research

NEW YORK (GenomeWeb) – Natera and the Feinstein Institute for Medical Research will partner to conduct research on cell-free circulating tumor DNA in order to detect, diagnose, and monitor cancer.

Natera will provide funding to the Feinstein Institute, which will contribute blood and tissue samples. Natera will develop technology for detecting ctDNA.

"Our vision is to enable cancer detection across multiple tumor types that will have the same key features as our prenatal tests: early, accurate, and non-invasive," said Natera CEO Matthew Rabinowitz in a statement.

Natera uses a targeted sequencing technology in its Panorama non-invasive prenatal test that analyzes SNPs in cell-free DNA to determine fetal aneuploidy. A similar sequencing strategy could be applied to circulating tumor DNA in cancer patients for monitoring the disease.

"Earlier cancer detection leads to better clinical outcomes," Peter Gregersen, director of the Feinstein Institute's Center for Genomics and Human Genetics, said in a statement. "[W]e are optimistic about the application of Natera's core technology to address the unique challenges in early cancer detection and monitoring."

The Scan

Could Mix It Up

The US Food and Drug Administration is considering a plan that would allow for the mixing-and-matching of SARS-CoV-2 vaccines and boosters, the New York Times says.

Closest to the Dog

New Scientist reports that extinct Japanese wolf appears to be the closest known wild relative of dogs.

Offer to Come Back

The Knoxville News Sentinel reports that the University of Tennessee is offering Anming Hu, a professor who was acquitted of charges that he hid ties to China, his position back.

PNAS Papers on Myeloid Differentiation MicroRNAs, Urinary Exosomes, Maize Domestication

In PNAS this week: role of microRNAs in myeloid differentiation, exosomes in urine, and more.