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Nanopore Sequencing Startup Nabsys Closes $4M Equity Round


Nabsys said today that it has closed a $4 million equity round, led by Point Judith Capital. The Slater Technology Fund and other previous investors also participated in the round.

The Providence, RI-based company said it will use the proceeds to further develop its nanopore-based DNA sequencing technology, which combines solid-state nanopores with sequencing-by-hybridization.

Originally, both approaches were independently pursued by researchers at Brown University, who founded two companies, Nabsys and GeneSpectrum. In late 2006, Nabsys acquired GeneSpectrum in an all-stock transaction (see In Sequence 1/9/2007).

The idea of the technology is to use electrically addressable nanoarrays to determine the position of probes hybridized to long fragments of DNA. By repeating the process with many probes from a library and comparing the hybridization patterns, the DNA sequence can be deduced.

Nabsys was founded in 2004 by Brown professors Xinsheng Sean Ling and Leon Cooper, and has exclusively licensed nanopore technology developed by Ling, a professor of physics.

In 2007, Nabsys won a two-year, $480,000 grant from the National Human Research Institute's Advanced Sequencing Technology program to develop its hybridization-assisted nanopore sequencing, or HANS, technology. Separately, Ling won a three-year, $820,000 grant under the same program that year to develop the technology.

The Scan

Could Mix It Up

The US Food and Drug Administration is considering a plan that would allow for the mixing-and-matching of SARS-CoV-2 vaccines and boosters, the New York Times says.

Closest to the Dog

New Scientist reports that extinct Japanese wolf appears to be the closest known wild relative of dogs.

Offer to Come Back

The Knoxville News Sentinel reports that the University of Tennessee is offering Anming Hu, a professor who was acquitted of charges that he hid ties to China, his position back.

PNAS Papers on Myeloid Differentiation MicroRNAs, Urinary Exosomes, Maize Domestication

In PNAS this week: role of microRNAs in myeloid differentiation, exosomes in urine, and more.