Massachusetts General Hospital's Diagnostic Molecular Pathology Laboratory and Translational Research Laboratory are planning to implement next-generation sequencing for screening cancer patients.

As a first step, MGH researchers are converting their SNaPshot assay, a multiplex-PCR and CE-based test that screens for hotspot mutations in 14 oncogenes, to NGS. Later, they plan to develop larger panels for clinical use to guide treatment and placement into clinical trials, and also for research use to help identify markers of drug response and resistance.

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In PLOS this week: locus linked to non-syndromic hearing loss, phylogenetic relationships of Klebsiella pneumoniae isolates, and more.

In a column at Nature, researcher Fyodor Kondrashov worries about the influence of politics on Russian science.

The term 'epigenetics' is being used by quacks to give them a veneer of science, writes Adam Rutherford at the Observer.

The NIH has issued a preliminary guidance for newborn dried blood spot research.