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Metagenomics-RAST server, Sequin 9.00, Cosmic 40

Researchers from Argonne National Laboratory, the University of Chicago, and San Diego State University have developed a metagenomics-RAST server, a public resource for the automated analysis of metagenomic sequence data generated by the 454 Life Sciences sequencing platform. The server, which is available here, generates phylogenetic and functional summaries of genomes by comparing the sequence data against protein and nucleotide databases. Researchers can upload data sets in the file format generated by the GS FLX instrument, either as raw reads or assembled contigs.

Sequin version 9.00 for Macintosh, PC/MS Windows, and Unix is available from the National Center for Biotechnology Information ftp site here. The software, a tool for uploading entries into nucleotide sequence databases, has been updated to comply with the latest version of the International Nucleotide Sequence Database Collaboration Feature Documentation.

COSMIC release 40, the Catalogue of Somatic Mutations in Cancer, is available here. The new version includes an update of existing genes, totaling almost 3,000 new mutations, as well as three additional genes that were recently identified as causes of cancer.

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more