Memorial Sloan-Kettering Cancer Center's diagnostic molecular pathology laboratory is developing a number of targeted sequencing assays to test for actionable cancer mutations and plans to run the first patient samples early next year, following certification by the New York State Department of Health.

The first assay will focus on solid tumors. It will use Illumina's TruSeq Amplicon Cancer Panel, which includes 212 amplicons representing mutational hotspots in 48 genes, including BRAF, KRAS, and EGFR, and will run on the Illumina MiSeq.

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