NEW YORK (GenomeWeb) – New research suggests features found in just a subset of individual cells from a tumor or its surroundings might offer insights into metastatic melanoma response to targeted therapies and immunotherapies.
A Broad Institute- and Dana-Farber Cancer Institute-led team used RNA sequencing to profile copy number changes and gene expression in thousands of individual tumor, stromal, endothelial, and immune cells isolated from fresh melanoma biopsies for 19 patients.