NEW YORK (GenomeWeb News) - Many roads lead to Rome, and so do many approaches to a DNA sequence. While several next-generation technologies track the incorporation of labeled nucleotides, others attempt to read DNA as it threads through a nanopore.
 
Now researchers at Stanford University have demonstrated yet another approach to single-molecule sequencing: They follow a single RNA polymerase enzyme and track its pauses as its travels along the DNA making RNA.
 

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