Cancer is like the mythical many-headed Hydra beast — cut off one head and two more grow back in its place. Like Hercules, researchers must take multiple approaches in their attempts to slay the beast. Complicating the matter is that cancer is not just a single disease, but a name under which many disorders fall, adding to the issues that researchers must deal with. I recently sat down with a group of cancer researchers to talk about the state of the field, and I was reminded that there will never be just one cure for cancer — each monstrous head needs its own remedy.