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NEW YORK (GenomeWeb) – Australian researchers have developed a deep sequencing-based strategy for characterizing resistance-related mutations in mixed bacterial populations.

The approach, known as resistance mutation sequencing (RM-seq), builds on the rationale behind low error amplicon sequencing (LEA-seq) — a targeted sequencing method that involves molecular barcoding. By tweaking that method to develop RM-seq, the team is able to look at several samples simultaneously.

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Nature News reports that gene therapy approaches are tackling sickle cell disease, but that the cost of treatment is a concern.

The Washington Post reports that a US Senate committee voted this week to approve the nomination of Stephen Hahn to lead the Food and Drug Administration.

One gene regulates hundreds of others to influence facial development, according to New Scientist.

In Nature this week: resources for single-cell analysis, little overlap in the microRNAs used by Salmonella and Shigella to infect host cells, and more.

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11
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Dec
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Dec
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This webinar will provide a first-hand look at how a clinical lab evolved its tumor profiling workflow from a targeted panel approach toward comprehensive genomic profiling.