NEW YORK (GenomeWeb News) – A large multi-institution consortium is identifying functional regions in mammalian genomes using low coverage genome sequencing and comparative genomics.

The 2X Mammalian Sequencing and Analysis Consortium has already sequenced nearly two dozen mammalian genomes at low coverage. By comparing these genomes to one another, and incorporating sequence information from published genome sequences, the group is pinpointing constrained regions in mammalian genomes with increasingly finer resolution.

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