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KAPA2G Fast Hot Start DNA polymerase, DNA Sequencing 2008 Report, MasterPure RNA purification kit, MultiGrade Gradient Thermal Cycler

Kapa Biosystems has released KAPA2G Fast Hot Start DNA polymerase, a second-generation polymerase engineered for speed, specificity, and performance. The enzyme was engineered using Kapa’s molecular evolution platform. The enzyme can synthesize DNA at a much faster rate than wild-type polymerases, extending DNA at a rate of 1 second per kilobase with no loss in performance, according to the company.

Research and Markets of Dublin has published a new report, entitled "DNA Sequencing 2008." The study focuses on the methods, instruments and software of DNA sequencing in medical research, agriculture and animal husbandry, and DNA testing and forensics application areas. Automated and non-automated DNA sequencing methods are analyzed. The report includes market data, segmentation, market size, key trends, M&A, product developments, industry forecasts, and corporate intelligence and lists 430 companies that are engaged in DNA sequencing services, instrumentation, R&D, and supply of products and services.

Epicentre Biotechnologies has launched a MasterPure RNA purification kit. The kit offers increased yields of total RNA, compared to conventional methods, according to the company. Gentle salt precipitation preserves microRNAs and other small RNAs that would be lost with a spin-column kit. Up to 25 micrograms of RNA can be obtained from 5 milligrams of mouse liver.

MIDSCI has released the MultiGene Gradient Thermal Cycler. The instrument features an easy-to-use interface for setting up protocols, the company claims. Protocols can be optimized by using a 12-row gradient which can be set up across the block. Several common protocols come pre-programmed and can be customized. The 96 x 0.2 milliliter block version is currently available and is compatible with all major brands of tubes, strips, and plates. The 96-well version will be upgradeable to a 60 x 0.5 milliliter block or a 384-well format.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.