This article was originally published March 24.

In collaboration with researchers from several academic and clinical research centers, a team from the Massachusetts-based enzyme development company Kapa Biosystems has been delving into potential problems and bottlenecks in preparing next-generation sequencing libraries — particularly those prepared from formalin-fixed, paraffin-embedded (FFPE) samples.

The effort is intended to improve library prep kits and their applications, Maryke Appel, technical director at Kapa, told In Sequence.

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