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Julian Parkhill, Carol Churcher, Harold Swerdlow, Jane Rogers, Peter Pohl, Marcus Benz, Christof von Kalle, Dirk Honold, Thomas Pohl

The Wellcome Trust Sanger Institute has appointed a new senior management team for DNA sequencing.
Julian Parkhill, head of the pathogen sequencing unit, has become director of sequencing. His role will be “to support the new management team, to give strategic direction, and to promote the important interactions between the institute’s faculty Investigators and the sequencing group,” according to the Sanger Institute.
Carol Churcher is the new head of sequencing operations. She is a senior manager in the pathogen sequencing unit and joined the institute when it was founded in 1993. Previously, she worked at the MRC Laboratory of Molecular Biology.
Harold Swerdlow has become head of sequencing technology. Until early 2006, he was senior director of research at Solexa, which became part of Illumina last year. Swerdlow holds a PhD in bioengineering from the University of Utah.
Jane Rogers, human sequencing and mapping project manager, left the Sanger Institute last year, according to an institute spokesperson. Rogers was also a member of the board of management.

Peter Pohl has become CEO of LifeCode, a new personal genomics spinoff from German sequencing service provider GATC Biotech (see feature article in this issue). He is also the CEO of GATC Biotech.
Pohl and Marcus Benz, GATC’s chief operating officer, are members of LifeCode’s board of directors. Christof von Kalle, a professor at the University of Freiburg, Germany; Dirk Honold, a professor at the University of Applied Science in Nuremberg, Germany; and Thomas Pohl, GATC’s CTO, are members of the company’s supervisory board, according to LifeCode’s website.

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.