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Joint Genome Institute, National Center for Biotechnology Information, Wellcome Trust Sanger Institute

The Department of Energy’s Joint Genome Institute has released IMG (Integrated Microbial Genomes) 2.1, a data-management system for microbial genome data. New features include model eukaryotic genomes, among them several yeast species, as well as the genomes of plasmids. IMG 2.1 includes information on 2,782 genomes — 661 bacterial, 34 archaeal, 24 eukaryotic, 1,661 bacterial phages, and 402 plasmids. Among these genomes, 2,524 are finished and 258 are draft.

The National Center for Biotechnology Information has released RefSeq 22, which includes 5,207,865 records, 3,438,099 proteins, and sequences from 4,187 different organisms.

The Wellcome Trust Sanger Institute’s Cancer Genome Project has released version 27 of the COSMIC (Catalog of Somatic Mutations in Cancer) database. The release includes upgrades to the website and new data, including resequencing studies and curated genes. COSMIC now contains data on more than 200,000 tumor samples and 400,000 individual experiments.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.