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Jackson Lab, Shriners Hospitals to Study Genetics of Pediatric Orthopedic Disorders

NEW YORK — The Jackson Laboratory and the Shriners Hospitals for Children said on Thursday that they have partnered to investigate the genetic causes of orthopedic disorders in pediatric patients.

Under the terms of the deal, Shriners Hospitals will perform next-generation sequencing on DNA samples from families at its 22 hospitals and outpatient locations in North America and from its international network of outreach clinics. Participants will include children with orthopedic conditions such as clubfoot, scoliosis, and osteogenesis imperfecta.

Jackson Lab investigators will analyze the data and develop mouse models with the same genetic variations as patients participating in the research program. The partners expect the work to advance the discovery of new treatments.

The deal with the Jackson Lab comes a few months after Shriners Hospitals established a new genomics institute in Tampa, Florida with Genome Medical.

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