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Integrated Microbial Genomes

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Version 2.4 of the Integrated Microbial Genomes data management system is now available from the Department of Energy’s Joint Genome Institute. IMG 2.4's content has been updated with new microbial genomes from the version 25 release of the National Center for Biotechnology Information Reference Sequence database. It contains a total of 3,637 genomes consisting of 818 bacterial, 50 archaeal, and 40 eukaryotic genomes; 2,042 viruses and bacterial phages; and 687 plasmids. Among these genomes, there are 3,334 finished and 303 draft genomes, of which 256 are genomes sequenced by DOE JGI. The IMG native controlled vocabulary of functional terms and pathways has been extended to 4,148 terms and 524 pathways, with 546,169 genes characterized using IMG terms. Functional annotation of genomes in IMG has been further enhanced through the computation of fused genes and by filling in various RNA genes missing from the original genome data sets. The next IMG update is scheduled for March 2008. Registration for September workshops on IMG, offered by JGI, is now open (click here).

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.