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Illumina, Integrated DNA Technologies Partner for NGS Library Prep

NEW YORK (GenomeWeb) – Integrated DNA Technologies and Illumina have partnered to provide multiplexed library preparation and target enrichment products for next-generation sequencing, IDT said today.

Under the agreement, the companies will develop a portfolio of indexed adapters to be manufactured by IDT. The adapters will be specifically designed for multiplex NGS, and will contain new sample index sequences optimized for use on Illumina systems including two-channel, patterned flow cell systems such as the NovaSeq series.

The adapters will also extend the number of unique dual indexes (UDI) from eight to 24, enabling higher multiplexing. The companies intend to further expand to 96 UDI kits in the fourth quarter this year. IDT also said that the optimized index codes are now available for incorporation into custom third-party NGS library prep adapter sets.

The partnership also includes a co-marketing agreement whereby the companies will provide a complete workflow for exome capture that couples Illumina's TruSeq and Nextera library prep kits with IDT's xGen Exome Research Panel, IDT said.

"Our work with IDT will help us to enhance the suite of library prep offerings and multiplexing capabilities available to users of Illumina sequencing platforms," Susan Tousi, senior vice president of product development at Illumina. "IDT is the optimal partner for this program because of their advanced nucleic acid synthesis capabilities."