Humans as Host

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The exact number of bacteria living in or on humans isn't known, though it is estimated to be around a trillion. In any case, the number of microbial cells in the human body outnumbers the human ones by a factor of 10. Those symbiotic microbes endow humans with otherwise unattainable metabolic capabilities, but also may contribute to human disease. What is certain, however, is that humans may really be classified as super-organisms — and ones that are mainly bacterial at that.

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This online seminar will outline a recent example of the use of molecular barcoding in combination with next-generation sequencing to detect somatic mosaicism in cancer patients.