Hopkins Researchers Show Exome Sequencing Provides New Route to Disease Genes | GenomeWeb

Based on exon resequencing data from a single cancer patient, researchers at Johns Hopkins University have discovered a new gene that, when mutated, predisposes its carrier to hereditary pancreatic cancer.

Maybe more important than the gene itself, which only explains a fraction of hereditary pancreatic cancer, is the sequencing-based approach the researchers used to pinpoint it, which they believe will be useful for finding new disease genes — especially once the cost of sequencing drops further.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Register for Free Content
You can still register for access to our free content.

In Science this week: deletion of one microRNA allows pluripotent stem cells to form embryonic and non-embryonic lineages, and more.

Arizona is planning to sue Theranos for "deceptive acts" and misrepresentations of its "capabilities and operation."

If confirmed as Department of Health and Human Services Secretary, Tom Price says he will divest himself of certain holdings, according to Stat News.

Oliver Smithies, who won the Nobel Prize in 2007, has died, the New York Times reports.