Helicos Talks About Homopolymer Troubles; Solution Paves Way to 2007 Beta-Testing | GenomeWeb
Helicos BioSciences last week for the first time publicly acknowledged that until last year it had been “unable to address homopolymer sequencing,” but said it has found a solution to this problem.
 
In a presentation at last week’s Advances in Genome Biology & Technology conference in Marco Island, Fla., Bill Efcavitch, Helicos’ senior vice president of product research and development, said the company has developed a proprietary nucleotide-polymerase pair where the nucleotides prevent the polymerase from adding more than one base per reacti

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