Julia Karow

This article, originally published Sept. 23, has been updated with comments from researchers.

Helicos BioSciences has demonstrated that its platform can be used to directly sequence single molecules of RNA, without prior conversion to cDNA, a capability the company said could have advantages for analyzing small amounts of RNA or short RNAs and for providing unbiased sampling of transcriptomes.

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In Nature this week: genomic analysis of high-grade serous ovarian cancer, and more.

The new Riken president outlines some of his plans for the institute.

The Guardian discusses whether big science projects are worth the loss of resources available for other scientific pursuits.

An NEJM update from the ClinVar team highlights the difficulties of interpreting genetic variants.