Helicos Sequences Yeast RNA Directly; Envisions Bias-Free Transcriptome Sequencing | GenomeWeb

Julia Karow

This article, originally published Sept. 23, has been updated with comments from researchers.

Helicos BioSciences has demonstrated that its platform can be used to directly sequence single molecules of RNA, without prior conversion to cDNA, a capability the company said could have advantages for analyzing small amounts of RNA or short RNAs and for providing unbiased sampling of transcriptomes.

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