Skip to main content
Premium Trial:

Request an Annual Quote

Helicos BioSciences Sells Sequencer to Dutch Medical Center

Premium

By Julia Karow

Helicos BioSciences said this week that it has sold a Helicos Genetic Analysis system to a group of Dutch medical centers, led by the Leiden University Medical Center.

The instrument, funded by a grant from the Netherlands Organization of Scientific Research, will be installed at LUMC's Leiden Genome Technology Center.

The center, headed by Johan den Dunnen, already has experience with next-generation sequencing: As of last year, it had two Illumina Genome Analyzers installed and had sequenced a human genome (see In Sequence 6/3/2008).

The sale follows a collaboration between Helicos and LUMC's forensic laboratory, which provided the company with DNA from human remains for analysis, a project the partners plan to publish. At a conference at Cold Spring Harbor Laboratory this fall, Helicos Vice President and Chief Scientific Officer Patrice Milos said that the DNA, extracted from teeth from an excavation at a church cemetery, dated back to the Middle Ages.

"Based on our initial results with another technology, we were not expecting to get much information from these highly degraded samples," said den Dunnen in a statement from the company. "Helicos was able to provide us with a surprisingly high proportion of human sequence information from these historical human remains, allowing us to determine their ancestry and relatedness for the first time."

Last week, Helicos said it has received sales orders for seven systems so far and has recognized revenue for two of these. In addition, it has three systems installed at academic institutions for scientific and commercial evaluation (see In Sequence 11/10/2009).

The Scan

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.

Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights

Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival.

CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood

A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system.

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.