NEW YORK (GenomeWeb) – A new study suggests cells in healthy esophageal skin tissue can progressively acquire a wide-range of cancer-related mutations with age, leading to mutant clones in more than half of the tissue tested by midlife.

"After studying the genetics, we were shocked to see that the healthy esophagus was riddled with mutations," senior author Philip Jones, a researcher with the Wellcome Trust Sanger Institute, said in a statement. "We discovered that by the time an individual reaches middle age, they probably have more mutant than normal cells."

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A new study finds that a placental protein linked with preeclampsia can be targeted by RNA silencing, according to the New Scientist.

A settlement is expected in a Duke University lawsuit hinging on using falsified data to win grants, Retraction Watch and Science report.

In PNAS this week: approach for analyzing the expression of endogenous retroviruses, circular RNAs that influence host-virus interactions, and more.

A phylogenetic analysis finds that the rare hemimastigotes form their own supra-kingdom, CBC reports.

Nov
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Sponsored by
Schott

This webinar will discuss how understanding the relative performance characteristics of glass and polymer substrates for in vitro diagnostic applications such as microarrays and microfluidics can help to optimize diagnostic performance.

Dec
03
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Advanced Cell Diagnostics

This webinar will demonstrate how a research team at the National Institutes of Health evaluated a novel in situ hybridization approach and applied it to study splice variants related to schizophrenia.

Dec
04
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Sophia Genetics

This webinar will discuss the use of clinical-grade exome analysis application in complex case investigations.

Dec
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PerkinElmer

This webinar describes a study that used two independent next-generation sequencing (NGS) platforms to gain insight into the impact of different types of aneuploidies during preimplantation genetic testing.