The Great Debate Rages On

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The battle between whole-genome and whole-exome sequencing has been waged for years. Researchers have discussed whether one approach or the other is better for different purposes — basic versus clinical research, complex versus Mendelian diseases, sequencing thousands of genomes versus just a few. Many researchers consider the debate both useful and practical, to help them clarify the uses of each method, how they could be used together, or how to best develop pipelines to analyze the data coming from them.

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In PNAS this week: rare variants linked to bleeding disorder, comparison of whole-exome and whole-genome sequencing, and more.

George Church tells The Sunday Times that his group has inserted some woolly mammoth genes into elephant cells.

A Scientific Reports editor resigns over a new policy at the journal allowing researchers to pay to fast track the peer review of their manuscripts, and poll.

The National Cancer Institute's Harold Varmus discusses the state of cancer research with the New York Times.

Apr
15
Sponsored by
WaferGen

This live online seminar will highlight recent trends in applying next-generation sequencing in the clinical setting, with a particular focus on oncology and rare disease.