The Great Debate Rages On

Premium

The battle between whole-genome and whole-exome sequencing has been waged for years. Researchers have discussed whether one approach or the other is better for different purposes — basic versus clinical research, complex versus Mendelian diseases, sequencing thousands of genomes versus just a few. Many researchers consider the debate both useful and practical, to help them clarify the uses of each method, how they could be used together, or how to best develop pipelines to analyze the data coming from them.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Browse our free articles
You can still register for access to our free content.

In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.