Many sequence analysis tools currently available don't adequately account for both the proximal and distal binding sites of cis-regulatory genomic regions, but, according to Gill Bejerano, they're not to blame. "These tools are perfect for what they were written for," — namely, microarray analysis — the assistant professor at Stanford University says. With the increasing emergence of next-generation sequencing data sets, researchers need an analytical tool "that really models next-generation sequencing data for what it really is," Bejerano says.

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