By Andrea Anderson

A multi-center team of researchers has sequenced exons from a large receptor family to identify potentially druggable melanoma-associated mutations that activate a signaling pathway already implicated as a potential therapeutic target for melanoma and other cancers.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.