NEW YORK (GenomeWeb) – In Nature Genetics, researchers from Sweden, the UK, and the US explored the potential risks of losing the Y chromosome from a subset of cells circulating in peripheral blood.

By doing array-based genotyping on DNA isolated from peripheral blood samples, the team looked at the incidence — and apparent consequences — of age-related Y chromosome loss in more than 1,150 elderly men.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.

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