Genome Organization Variation Uncovered With Molecular Mapping Methods

Feb 21, 2019

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NEW YORK (GenomeWeb) – Genome organization can vary significantly within cells and by allele, according to a team from the National Cancer Institute, Harvard University, the University of Massachusetts, and the Massachusetts Institute of Technology.

"Our findings reveal a remarkably high degree of cell-to-cell and allele-to-allele heterogeneity in spatial genome organization," senior author Tom Misteli, director of NCI's Center for Cancer Research, and his co-authors wrote.

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