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Genome Express, COSMIC 35

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Innovadyne Technologies has launched Genome Express, a high-throughput, 16-channel dispenser for use in genomic applications, such as setting up PCR and sequencing reactions. The new system can perform 384 1-microliter reaction setups, including template transfers and master mix addition, in less than 10 minutes. According to the company, the instrument complements existing PCR and sequencing platforms as well as emerging high-throughput systems that require lower volume additions.
 

 
Cosmic release 35 is now available here. The new release contains curations for four new tumor suppressor genes, and further curation of EWSR1/FLI1 gene fusions in Ewing's sarcoma.

The Scan

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.

Lupus Heterogeneity Highlighted With Single-Cell Transcriptomes

Using single-cell RNA sequencing, researchers in Nature Communications tracked down immune and non-immune cell differences between discoid lupus erythematosus and systemic lupus erythematosus.

Rare Disease Clues Gleaned From Mobile Element Insertions in Exome Sequences

With an approach called MELT, researchers in the European Journal of Human Genetics uncovered mobile element insertions in exomes from 3,232 individuals with or without developmental or neurological abnormalities.

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.