GenBank release 165.0 is now available here via FTP from the National Center for Biotechnology Information. It contains data as of April 15. The new release contains approximately 89 billion base pairs and 86 million entries from non-WGS and non-CON sequences, and 110 billion base pairs and 27 million entries from WGS sequences. Uncompressed, the 165.0 release flat files require about 332 GB for sequence files only. The ASN.1 data require approximately 305 GB.
 

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.

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