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GenBank 164.0, GATC Barcoding System

GenBank release 164.0 is available here via FTP from the National Center for Biotechnology Information. It contains data as of Feb. 12. The new release contains 85,759,586,764 base pairs and 82,853,685 entries. Uncompressed, the 164.0 release flat files require about 321 GB for sequence files only. The ASN.1 data require approximately 295 GB.

GATC Biotech has introduced a cross-platform barcoding system for multi-sample sequencing on Roche’s 454 GS FLX and Illumina’s Genome Analyzer. The barcodes are available to its next-generation sequencing service customers. According to the company, the technique is highly efficient, tagging 99.9 percent of sequences successfully. GATC has already used the barcodes in BAC sequencing projects with 50 individual tags using the GS FLX. The company plans to use the barcodes with its ABI SOLiD system as well.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.