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GATC Wins €750,000 Contract to Sequence Pediatric Brain Tumors for German ICGC Project

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This story was originally published May 20

GATC Biotech said last week that is has won a €750,000 ($930,000) contract from a German research consortium to sequence pediatric brain tumors for a project that is part of the International Cancer Genome Consortium.

Under the contract, the German sequencing service provider will use Illumina sequencing technology, including a HiSeq 2000 instrument the company received this week, to sequence the genomes of brain tumors and matching normal controls from the same patient at 30-fold coverage. It expects to provide the data to the German Cancer Research Center, DKFZ, which manages the project, this fall.

Last year, the PedBrain Tumor Consortium, which includes researchers from seven institutions in Germany, won €15 million ($18.6 million) in funding over five years from the German Federal Ministry for Education and Research and German Cancer Aid, a charity, to study the genomics of two childhood brain cancers, medulloblastoma and pylocytic astrocytoma (IS 12/15/2009).

Under the project, which is part of the ICGC, the researchers plan to comprehensively analyze 300 tumor samples and matched controls, with the goal to discover new therapeutic targets, diagnostic biomarkers, and predictors of treatment response.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.