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Funding Update: Jun 16, 2009

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Sequencing-Related NIH Funding, FY 2009, March 27 — June 15, 2009

The Temporal Reconfiguration of Regulatory Networks: From Yeast to Cancer
Principal Investigator: Aviv Regev
Institution: Massachusetts Institute of Technology
Start date: Sept 30, 2008
End date: July 31, 2013
FY 2009 funding: NA
NIH Institute: Office of the Director


High Throughput DNA Sequencer
Principal Investigator: Suzanne Sandmeyer
Institution: University of California, Irvine
Start date: May 1, 2009
End date: April 30, 2010
FY 2009 funding: $500,000
NIH Institute: National Center for Research Resources


Illumina Genome Analysis System
Principal Investigator: Michael Sussman
Institution: University of Wisconsin Madison
Start date: April 1, 2009
End date: March 31, 2010
FY 2009 funding: $495,000
NIH Institute: National Center for Research Resources


Illumina Genome Analyzer II
Principal Investigator: David Bishop
Institution: Mount Sinai School of Medicine of New York University
Start date: April 1, 2009
End date: March 31, 2010
FY 2009 funding: $338,000
NIH Institute: National Center for Research Resources


Intellectual Property Challenges for the Development of Genomic Diagnostics
Principal Investigator: Subhashini Chandrasekharan
Institution: Duke University
Start date: April 1, 2009
End date: March 31, 2011
FY 2009 funding: $78,000
NIH Institute: National Human Genome Research Institute


Massively Parallel Analysis of Integration in Therapeutic Gene Transfer
Principal Investigator: Frederic Bushman
Institution: University of Pennsylvania
Start date: June 15, 2009
End date: May 31, 2013
FY 2009 funding: NA
NIH Institute: National Institute of Allergy and Infectious Diseases


The Human Virome in Children and its Relationship to Febrile Illness
Principal Investigator: Gregory Storch
Institution: Washington University
Start date: May 8, 2009
End date: April 30, 2010
FY 2009 funding: $954,385
NIH Institute: National Institute of Allergy and Infectious Diseases


Molecular and Informatics Methods for Whole-Genome Mutational Profiling
Principal Investigators: Marc-Jan Gubbels, Gabor Marth
Institution: Boston College
Start date: June 1, 2009
End date: May 31, 2011
FY 2009 funding: NA
NIH Institute: National Institute of Allergy and Infectious Diseases


High Throughput Genome Sequencer for Organ Building
Principal Investigator: Richard Maas
Institution: Brigham and Women's Hospital
Start date: March 27, 2009
End date: Feb 28, 2010
FY 2009 funding: $498,740
NIH Institute: National Center for Research Resources


Somatic Mutation Discovery in Lung Squamous Cell Carcinoma
Principal Investigator: Alexis Ramos
Institution: Harvard University Medical School
Start date: Nov 16, 2008
End date: Nov 15, 2011
FY 2009 funding: NA
NIH Institute: National Cancer Institute

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Technology for Sensitive and Reliable Mutational Profiling in Pancreatic Cancer
Principal Investigator: Mike Makrigiorgos
Institution: Dana-Farber Cancer Institute
Start date: April 1, 2009
End date: March 31, 2012
FY 2009 funding: $227,040
NIH Institute: National Cancer Institute


An Efficient Lightweight Environment for Biomedical Computation
Principal Investigator: Anton Nekrutenko
Institution: Pennsylvania State University-University Park
Start date: May 1, 2009
End date: Feb. 29, 2012
FY 2009 funding: $479,349
NIH Institute: National Human Genome Research Institute


High-Throughput Sequencing Instrument for Stanford Cancer Center
Principal Investigator: Patrick Brown
Institution: Stanford University
Start date: April 19, 2009
End date: April 18, 2010
FY 2009 funding: $500,000
NIH Institute: National Center for Research Resources


Metagenomic Study of the Human Skin Microbiome Associated with Acne
Principal Investigators: Huiying Li, Robert Modlin
Institution: University of California, Los Angeles
Start date: May 15, 2009
End date: April 30, 2010
FY 2009 funding: NA
NIH Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases


A New Methodology to Decipher Three-Dimensional Genome Structure
Principal Investigator: Kenichi Noma
Institution: Wistar Institute
Start date: Sept 30, 2008
End date: Aug 31, 2013
FY 2009 funding: NA
NIH Institute: Office of the Director


Dissection of Two Rheumatoid Arthritis Risk Loci from Genome-Wide Studies
Principal Investigator: Robert Plenge
Institution: Brigham and Women's Hospital
Start date: May 15, 2009
End date: April 30, 2014
FY 2009 funding: NA
NIH Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases


Massively Parallel Sequencing Technology for Cancer Epigenome
Principal Investigator: Lanlan Shen
Institution: University of Texas MD Anderson Cancer Center
Start date: April 1, 2009
End date: March 31, 2011
FY 2009 funding: $169,400
NIH Institute: National Cancer Institute


Massively Parallel Sequencing of the Diapause Transcriptome in Aedes albopictus
Principal Investigators: Peter Armbruster, David Denlinger
Institution: Georgetown University
Start date: June 19, 2009
End date: May 31, 2011
FY 2009 funding: NA
NIH Institute: National Institute of Allergy and Infectious Diseases


Unraveling the Genetic Architecture of Very High HDL cholesterol though Transcrip[tome Resequencing]
Principal Investigator: Michael Miller
Institution: University of Maryland Baltimore
Start date: May 1, 2009
End date: April 30, 2011
FY 2009 funding: $157,500
NIH Institute: National Heart, Lung, and Blood Institute


Algorithmic Strategies for Detecting Structural Variation in Genomes
Principal Investigator: Vineet Bafna
Institution: University of California, San Diego
Start date: April 1, 2009
End date: Feb 28, 2013
FY 2009 funding: $330,660
NIH Institute: National Human Genome Research Institute

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High-throughput Genetic Analyzer Upgrade for Comparative Population Genomics
Principal Investigator: Adalgisa Caccone
Institution: Yale University
Start date: May 1, 2009
End date: April 30, 2010
FY 2009 funding: $92,429
NIH Institute: National Center for Research Resources


E. coli Quiescent Systems for Mammalian Expression of Unclonable DNA
Principal Investigator: Ronald Godiska
Institution: Lucigen, Middleton, Wis.
Start date: July 10, 2008
End date: Dec 31, 2009
FY 2009 funding: N/A
NIH Institute: National Human Genome Research Institute


Analyzing Allele Specific Gene Expression and Regulation in C. Albicans.
Principal Investigator: Sadie Marjani
Institution: Yale University
Start date: Oct 20, 2009
End date: N/A
FY 2009 funding: $50,054
NIH Institute: National Institute of General Medical Sciences


Massively Parallel Single Cell Genomics of the Human Microbiome
Principal Investigator: David Mead
Institution: Lucigen, Middleton, Wis.
Start date: Sept 1, 2008
End date: Feb 28, 2010
FY 2009 funding: N/A
NIH Institute: National Institute of Allergy and Infectious Diseases


Genomics/Bioinformatics Core
Principal Investigator: Stanley Nelson
Institution: University of California Los Angeles
Start date: N/A
End date: N/A
FY 2009 funding: N/A
NIH Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases


Evaluation of the Cutaneous Microbiome in Psoriasis
Principal Investigator: Martin Blaser
Institution: New York University School of Medicine
Start date: May 7, 2009
End date: April 30, 2010
FY 2009 funding: N/A
NIH Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases


High Throughput Microrepository for Genetic Materials
Principal Investigator: Robert Haushalter
Institution: Parallel Synthesis Technologies, Santa Clara, Calif.
Start date: Sept. 1, 2008
End date: Feb. 28, 2010
FY 2009 funding: N/A
NIH Institute: National Human Genome Research Institute


New Light Technology for Inducing Fluorescence for Bioanalysis
Principal Investigator: Claudia Jaffe
Institution: Lumencor, Beaverton, Ore.
Start date: Aug. 1, 2008
End date: Jan. 31, 2010
FY 2009 funding: N/A
NIH Institute: National Institute of General Medical Sciences


Rise of HIV-1 Low-Level Viremia as an Early Predictor of Virologic Rebound
Principal Investigator: John McKinnon
Institution: University of Pittsburgh at Pittsburgh
Start date: June 5, 2009
End date: May 31, 2011
FY 2009 funding: N/A
NIH Institute: National Institute of Allergy and Infectious Diseases


Application of 454 Sequencing to Cancer Epigenomics
Principal Investigator: Huidong Shi
Institution: Medical College of Georgia
Start date: May 1, 2009
End date: April 30, 2012
FY 2009 funding: $321,334
NIH Institute: National Cancer Institute

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Computer Cluster and Storage to Support Whole Genome Sequencing and Analysis
Principal Investigator: Eric Sobel
Institution: University of California, Los Angeles
Start date: May 14, 2009
End date: May 13, 2010
FY 2009 funding: N/A
NIH Institute: National Center for Research Resources


Construction of a Reference Sequence Data Set for The Human Microbiome Project
Principal Investigator: Robert Strausberg
Institution: J. Craig Venter Institute
Start date: May 22, 2009
End date: April 30, 2011
FY 2009 funding: N/A
NIH Institute: National Institute of Allergy and Infectious Diseases


Sequencing the Human Microbiome
Principal Investigator: George Weinstock
Institution: Washington University
Start date: My 22, 2009
End date: April 30, 2013
FY 2009 funding: N/A
NIH Institute: National Human Genome Research Institute


High-performance Computing System for Bioinformatics
Principal Investigator: Huntington Willard
Institution: Duke University
Start date: June 1, 2009
End date: May 31, 2010
FY 2009 funding: N/A
NIH Institute: National Center for Research Resources

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.