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Francis Collins, Alan Guttmacher, Roch Kelly, Heiner Dreismann

Francis Collins, director of the National Human Genome Research Institute, said last week that he will step down from his post on Aug. 1 to focus on “writing projects and other professional opportunities.” Collins has been director of NHGRI since April 1993 and led the Human Genome Project to its completion in 2003. He also guided a number of follow-up initiatives, such as the International HapMap Project, the Encyclopedia of DNA Elements, the Knockout Mouse Project, the Mammalian Gene Collection, the Cancer Genome Atlas, the Molecular Libraries Initiative, and the Human Microbiome Project. In addition, Collins founded an intramural program in genomics within the National Institutes of Health in 1993.
Alan Guttmacher, deputy director of NHGRI, will be appointed as acting director of the institute on Aug. 1. NIH said that it will soon begin a formal search process for a permanent NHGRI director.

Roch Kelly has become chief operating officer of RainDance Technologies, the company said this week. He joins RainDance from Synarc, where he was vice president of clinical operations. Previously, he was chief operating officer and chief financial officer at Protedyne, vice president of clinical operations and worldwide business at Parexel International, and executive director of manufacturing operations at Chiron Diagnostics. Kelly holds an MBA from Syracuse University and a BSc in finance from Miami University in Ohio.


Heiner Dreismann has become a director of Med BioGene, the company said last week. He will chair MBI's strategy committee. Dreismann is the former CEO of Roche Molecular Diagnostics, a business area of Roche Diagnostics. Prior to that, he held other senior positions within Roche. Dreismann holds a PhD in microbiology and molecular biology and a master’s degree in biology from the University of Münster in Germany.

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.